Invention Grant
US08642616B2 Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts
有权
较低的剂量强度咪喹莫特配方和用于治疗生殖器和肛周疣的短剂量方案
- Patent Title: Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts
- Patent Title (中): 较低的剂量强度咪喹莫特配方和用于治疗生殖器和肛周疣的短剂量方案
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Application No.: US13559473Application Date: 2012-07-26
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Publication No.: US08642616B2Publication Date: 2014-02-04
- Inventor: Michael T. Nordsiek , Jefferson J. Gregory
- Applicant: Michael T. Nordsiek , Jefferson J. Gregory
- Applicant Address: US AZ Scottsdale
- Assignee: Medicis Pharmaceutical Corporation
- Current Assignee: Medicis Pharmaceutical Corporation
- Current Assignee Address: US AZ Scottsdale
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K31/44
- IPC: A61K31/44

Abstract:
Pharmaceutical formulations and methods for the topical or transdermal delivery of 1isobutyl-1H-imidazo[4,5-c]-quinolin-4-amine or 1-(2-methylpropyl)-1H-imidazo[4,5 c]quinolin-4-amine, i.e., imiquimod, to treat genital/perianal warts with shorter durations of therapy than currently prescribed for the commercially available for Aldara® 5% imiquimod cream, as now approved by the U.S. Food & Drug Administration (“FDA”), are disclosed and described. More specifically, lower dosage strength imiquimod formulations to deliver an efficacious dose of imiquimod for treating genital/perianal warts with an acceptable safety profile and dosing regimens that are shorter and more convenient for patient use than the dosing regimen currently approved by the U.S. Food & Drug Administration (“FDA”) for Aldara® 5% imiquimod cream to treat genital/perianal warts are also disclosed and described.
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