Invention Grant
- Patent Title: Quinolone compound and pharmaceutical composition
- Patent Title (中): 喹诺酮化合物和药物组合物
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Application No.: US13590227Application Date: 2012-08-21
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Publication No.: US08642619B2Publication Date: 2014-02-04
- Inventor: Kenji Otsubo , Yuji Ochi , Masami Nakai , Atsushi Mori
- Applicant: Kenji Otsubo , Yuji Ochi , Masami Nakai , Atsushi Mori
- Applicant Address: JP Tokyo
- Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2007-150819 20070606
- Main IPC: A61K31/04
- IPC: A61K31/04 ; C07D215/38

Abstract:
The present invention provides a quinolone compound represented by General Formula (1) or a salt thereof, wherein R1 represents a hydrogen atom, etc.; R2 represents a hydrogen atom, etc.; R3 represents a phenyl group optionally being substituted with one or more substituents, etc.; R4 represents a halogen atom; R5 represents a hydrogen atom or halogen atom; R6 represents a hydrogen atom; and R7 represents a hydroxyl group, etc. The quinolone compound have a functional improvement effect, which suppresses progression of neurological dysfunction by inhibiting the chronic progression of Parkinson's disease or protecting dopamine neurons from the disease etiology, thereby prolonging the period before first administration begins.
Public/Granted literature
- US20120316168A1 QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION Public/Granted day:2012-12-13
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