Invention Grant
- Patent Title: Naphthylacetic acids
- Patent Title (中): 萘乙酸
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Application No.: US12614485Application Date: 2009-11-09
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Publication No.: US08642629B2Publication Date: 2014-02-04
- Inventor: Li Chen , Fariborz Firooznia , Paul Gillespie , Yun He , Tai-An Lin , Eric Mertz , Sung-Sau So , HongYing Yun , Zhenshan Zhang
- Applicant: Li Chen , Fariborz Firooznia , Paul Gillespie , Yun He , Tai-An Lin , Eric Mertz , Sung-Sau So , HongYing Yun , Zhenshan Zhang
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/02

Abstract:
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein W, X, Y, and R1-R7 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
Public/Granted literature
- US20100125058A1 NAPHTHYLACETIC ACIDS Public/Granted day:2010-05-20
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