Invention Grant
- Patent Title: CXCR2 antagonists
- Patent Title (中): CXCR2拮抗剂
-
Application No.: US12337970Application Date: 2008-12-18
-
Publication No.: US08642643B2Publication Date: 2014-02-04
- Inventor: Stephanie Hachtel , Juergen Dedio , Josef Pernerstorfer , Stephen Shimshock , Carolina Lanter , Raymond Kosley
- Applicant: Stephanie Hachtel , Juergen Dedio , Josef Pernerstorfer , Stephen Shimshock , Carolina Lanter , Raymond Kosley
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP06013321 20060628
- Main IPC: A01N43/02
- IPC: A01N43/02 ; A61K31/38 ; A01N43/12 ; A01N43/40 ; A61K31/44 ; C07D333/00 ; C07D409/02 ; C07D409/00 ; C07D411/00

Abstract:
The invention relates to compounds of the formula I in which R1, R2, A, B, X and Y have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
Public/Granted literature
- US20090258906A1 CXCR2 ANTAGONISTS Public/Granted day:2009-10-15
Information query
IPC分类: