Invention Grant
- Patent Title: Modulation of the activity and differentiation of cells expressing the osteoclast-associated receptor
- Patent Title (中): 调节表达破骨细胞相关受体的细胞的活性和分化
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Application No.: US13122637Application Date: 2009-10-06
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Publication No.: US08642728B2Publication Date: 2014-02-04
- Inventor: John Trowsdale , Alexander Barrow , Richard Farndale
- Applicant: John Trowsdale , Alexander Barrow , Richard Farndale
- Applicant Address: GB Cambridge
- Assignee: Cambridge Enterprise Ltd.
- Current Assignee: Cambridge Enterprise Ltd.
- Current Assignee Address: GB Cambridge
- Agent Michael J. Brignati
- International Application: PCT/GB2009/002382 WO 20091006
- International Announcement: WO2010/040998 WO 20100415
- Main IPC: A61K38/39
- IPC: A61K38/39 ; A61K38/17 ; C07K14/78
Abstract:
This invention relates to the finding that collagen peptides bind to the osteoclast-associated receptor (OSCAR) and stimulate the activation and/or differentiation of OSCAR expressing cells, such as osteoclasts and osteoclast precursor cells. Collagen peptides are described which may be useful in the modulation of the differentiation and/or activation of OSCAR expressing cells, for example in the treatment of bone defects and disorders characterized by altered differentiation and/or activation of OS-CAR expressing cells.
Public/Granted literature
- US20120028903A1 MODULATION OF THE ACTIVITY AND DIFFERENTIATION OF CELLS EXPRESSING THE OSTEOCLAST-ASSOCIATED RECEPTOR Public/Granted day:2012-02-02
Information query
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