Invention Grant
- Patent Title: Genetic modification of targeted regions of the cardiac conduction system
- Patent Title (中): 心脏传导系统目标区域的遗传修饰
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Application No.: US13224593Application Date: 2011-09-02
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Publication No.: US08642747B2Publication Date: 2014-02-04
- Inventor: Vinod Sharma , Walter H. Olson
- Applicant: Vinod Sharma , Walter H. Olson
- Applicant Address: US MN Minneapolis
- Assignee: Medtronic, Inc.
- Current Assignee: Medtronic, Inc.
- Current Assignee Address: US MN Minneapolis
- Agency: Mueting Raasch & Gebhardt PA
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/00 ; C07H21/02
Abstract:
Disclosed are methods and systems for preventing or treating cardiac dysfunction, particularly cardiac pacing dysfunction by genetic modification of the conduction system of the heart. In one embodiment, the invention provides a method of genetically modifying the cells by delivering to the cells one or more coding sequence in a genetic construct capable of modifying the expression of ion channels of the cells.
Public/Granted literature
- US20120065253A1 GENETIC MODIFICATION OF TARGETED REGIONS OF THE CARDIAC CONDUCTION SYSTEM Public/Granted day:2012-03-15
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