An iPad and keypad cover structure includes an iPad leather cover, a cover board, and a foldable member to connect the iPad leather cover and the cover board. The cover board has a fold line at a central portion thereof and at least one fixing tongue at an outer edge thereof. A keypad is provided on an inner side of the cover board. The iPad leather cover has a chamber at an inner side thereof and at least one transverse engaging piece disposed on an outer side thereof. The fixing tongue is inserted in the engaging piece of the iPad leather cover to secure the iPad and keypad cover structure when the cover board is folded face-to-face or back-to-back relative to the iPad leather cover. An iPad and the keypad are received therein face-to-face when the cover board is folded face-to-face relative to the iPad leather cover.