An apparatus for use in performing imaging a region of a patient's body including a first imaging system for acquiring first imaging information including a first region of interest using a first imaging modality, a second imaging system for acquiring second imaging information including a second region of interest using a second imaging modality, a first drive system for selectively moving at least a portion of one of the first and second imaging systems relative to an imaging reference frame, wherein the first drive system is operative to move one of the first and second imaging systems independent of movement of the other of the first and second imaging systems. A method for imaging a region of a patient's body including acquiring first imaging information corresponding to a first region of interest using a first imaging modality, acquiring second imaging information corresponding to a second region of interest using a second imaging modality, selectively moving at least a portion of one of a first and/or second imaging system relative to an imaging reference frame, wherein selectively moving comprises operating moving one of the first and second imaging systems independent of movement of the other of the first and second imaging systems.