Described is a method for image registration utilizing particle swarm optimization (PSO). In order to register two images, a set of image windows is first selected from a test image and transformed. A plurality of software agents is configured to operate as a cooperative swarm to optimize an objective function, and an objective function is then evaluated at the location of each agent. The objective function represents a measure of the difference or registration quality between at least one transformed image window and a reference image. The position vectors representing the current individual best solution found and the current global best solution found by all agents are then updated according to PSO dynamics. Finally, the current global best solution is compared with a maximum pixel value which signifies a match between an image window and the reference image. A system and a computer program product are also described.