A system for electronically recording and sharing medical data is provided, the system comprising an electronic source document, wherein the electronic source document comprises a database. In one particular embodiment, the medical data comprise clinical study data, and in another the medical data comprise patient specific data. In some embodiments, the system includes means for defining data parameters and storing the data parameters within the electronic source document, as well as a browser-based means for entering data into the electronic source document and storing the data therein. In a further embodiment, the system comprises means for one or more users of the system to view stored data. In a still further embodiment, means for one or more users to amend data stored in the electronic source document is provided, and in yet another embodiment the system comprises means for creating and maintaining an audit trail when one or more of the users amends data stored in the electronic source document. In other embodiments, the system further comprises an application specific navigation tool; in some embodiments, the application specific tool comprises a graphical user interface. Appropriate methods of using the system are also provided.