A pistol holster is disclosed that permits a pistol to be loaded while within the holster. To effect this, the holster body containing the lower portion of a pistol, slides downward relative to a slide bar component that holds the breach block of the pistol, allowing a live round of ammunition to be loaded into the pistol's firing chamber with a single hand action, to make the pistol ready for firing. The holster also contains one or more locks to prevent unintentional removal of the pistol from the holster.