Invention Grant
- Patent Title: Agents and method for treating inflammation-related conditions and diseases
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Application No.: US13766733Application Date: 2013-02-13
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Publication No.: US08647616B2Publication Date: 2014-02-11
- Inventor: David J. Baylink , Kin-Hing William Lau , Xuezhong Qin
- Applicant: Loma Linda University
- Applicant Address: US CA Loma Linda
- Assignee: Loma Linda University
- Current Assignee: Loma Linda University
- Current Assignee Address: US CA Loma Linda
- Agency: Sheldon Mak & Anderson PC
- Agent David A. Farah
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K35/26 ; A61K35/28
Abstract:
Gene-modified, inflammation-specific monocytes that comprise a 1-alpha-hydroxylase gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme when the monocytes transdifferentiate into gene-modified, inflammation-specific macrophages. Gene-modified, inflammation-specific macrophages that comprise a 1-alpha-hydroxylase gene. A method for treating one or more than one inflammation-related condition or disease, the method comprising administering gene-modified, inflammation-specific monocytes that comprise a 1-alpha-hydroxylase gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme when the monocytes transdifferentiate into gene-modified, inflammation-specific macrophages.
Public/Granted literature
- US20130209477A1 AGENTS AND METHOD FOR TREATING INFLAMMATION-RELATED CONDITIONS AND DISEASES Public/Granted day:2013-08-15
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