Invention Grant
- Patent Title: Anti-CD154 antibodies
- Patent Title (中): 抗CD154抗体
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Application No.: US11572647Application Date: 2005-07-26
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Publication No.: US08647625B2Publication Date: 2014-02-11
- Inventor: Herman Van Vlijmen , Alexey Alexandrovic Lugovskoy , Karl J. M. Hanf
- Applicant: Herman Van Vlijmen , Alexey Alexandrovic Lugovskoy , Karl J. M. Hanf
- Applicant Address: US MA Cambridge
- Assignee: Biogen Idec MA Inc.
- Current Assignee: Biogen Idec MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi LLP
- International Application: PCT/US2005/026320 WO 20050726
- International Announcement: WO2006/033702 WO 20060330
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28

Abstract:
The present invention provides peptides, and fragments thereof, and antibodies, or fragments thereof comprising the same, wherein the peptide comprises at least one amino acid substitution compared to wild type 5c8 antibody. The present invention also provides compositions and methods of treating CD154-related diseases or disorders in a subject.
Public/Granted literature
- US20080305116A1 Anti-Cd154 Antibodies Public/Granted day:2008-12-11
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