Invention Grant
US08647631B2 Pharmaceutical composition of an antigenic tau peptide reconstituted in a liposome and related antibodies and cell lines
有权
在脂质体中重构的抗原性tau肽的药物组合物和相关的抗体和细胞系
- Patent Title: Pharmaceutical composition of an antigenic tau peptide reconstituted in a liposome and related antibodies and cell lines
- Patent Title (中): 在脂质体中重构的抗原性tau肽的药物组合物和相关的抗体和细胞系
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Application No.: US13262793Application Date: 2010-04-01
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Publication No.: US08647631B2Publication Date: 2014-02-11
- Inventor: Andrea Pfeifer , Andreas Muhs , Fred Van Leuven , Maria Pihlgren
- Applicant: Andrea Pfeifer , Andreas Muhs , Fred Van Leuven , Maria Pihlgren
- Applicant Address: BE Leuven CH Lausanne
- Assignee: Katholieke Universiteit Leuven,AC Immune S.A.
- Current Assignee: Katholieke Universiteit Leuven,AC Immune S.A.
- Current Assignee Address: BE Leuven CH Lausanne
- Agency: Johnson, Marcou & Isaacs, LLC
- Agent F. Brent Nix
- Priority: EP09157303 20090403
- International Application: PCT/EP2010/054418 WO 20100401
- International Announcement: WO2010/115843 WO 20101014
- Main IPC: A61K39/385
- IPC: A61K39/385 ; A61K38/10 ; A61K39/00 ; A61K9/127
Abstract:
The present invention is related to methods and pharmaceutical compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to pharmaceutical composition comprising an antigenic peptide, particularly an antigenic phospho-peptide mimicking a major pathological phospho-epitope of protein tau, for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease.
Public/Granted literature
- US20120183599A1 Pharmaceutical Composition Public/Granted day:2012-07-19
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