Invention Grant
- Patent Title: Synergistic attenuation of vesicular stomatitis virus, vectors thereof and immunogenic compositions thereof
- Patent Title (中): 囊泡性口炎病毒的协同减弱，其载体及其免疫原性组成
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Application No.: US13600289Application Date: 2012-08-31
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Publication No.: US08647638B2Publication Date: 2014-02-11
- Inventor: David Kirkwood Clarke , Roger Michael Hendry , Stephen A. Udem , Christopher Lee Parks
- Applicant: David Kirkwood Clarke , Roger Michael Hendry , Stephen A. Udem , Christopher Lee Parks
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent Victoria S. Molenda
- Main IPC: A61K39/205
- IPC: A61K39/205 ; A61K39/12 ; C12N7/01 ; C12N15/63
Abstract:
The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV), More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.
Public/Granted literature
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