Invention Grant
- Patent Title: Farnesoid-X-receptor antagonist as a vaccine adjuvant
- Patent Title (中): 法呢基-X受体拮抗剂作为疫苗佐剂
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Application No.: US13121449Application Date: 2009-09-26
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Publication No.: US08647643B2Publication Date: 2014-02-11
- Inventor: Bakulesh Mafatlal Khamar , Indravadan Ambalal Modi , Rajiv Indravadan Modi
- Applicant: Bakulesh Mafatlal Khamar , Indravadan Ambalal Modi , Rajiv Indravadan Modi
- Applicant Address: IN Ahmedabad
- Assignee: Cadila Pharmaceuticals, Ltd
- Current Assignee: Cadila Pharmaceuticals, Ltd
- Current Assignee Address: IN Ahmedabad
- Agency: Burns & Levinson, LLP
- Priority: IN2080/MUM/2008 20080929
- International Application: PCT/IB2009/006950 WO 20090926
- International Announcement: WO2010/035119 WO 20100401
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/02 ; A61K39/12 ; A61K39/002 ; A61K47/28
Abstract:
The invention provides novel adjuvants and pharmaceutical composition comprising of an adjuvant alone. The invention also provides novel vaccine compositions comprising of an antigen and a novel adjuvant. The novel adjuvant as per present invention is farnesoid-X-receptor (FXR) antagonist. The invention also relates to an adjuvant for variety of antigens. The adjuvant improves antibody production specific to incorporated antigen. The adjuvant also induces cell mediated immune response.
Public/Granted literature
- US20110182939A1 Vaccine Adjuvants Public/Granted day:2011-07-28
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