Invention Grant
- Patent Title: Artificial tissue constructs comprising alveolar cells and methods for using the same
- Patent Title (中): 包含肺泡细胞的人造组织构建体及其使用方法
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Application No.: US12173921Application Date: 2008-07-16
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Publication No.: US08647837B2Publication Date: 2014-02-11
- Inventor: Ayesha Mahmood , Anatoly Kachurin , William Warren , Russell Higbee
- Applicant: Ayesha Mahmood , Anatoly Kachurin , William Warren , Russell Higbee
- Applicant Address: US FL Orlando
- Assignee: Sanofi Pasteur Vaxdesign Corp.
- Current Assignee: Sanofi Pasteur Vaxdesign Corp.
- Current Assignee Address: US FL Orlando
- Agency: Roylance, Abrams, Berdo & Goodman LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53 ; C12Q1/02
Abstract:
The present invention comprises artificial tissue constructs that serve as in vitro models of mammalian lung tissue. The artificial tissue constructs of the present invention comprise functionally equivalent in vitro tissue scaffolds that enable immunophysiological function of the lung. The constructs can serve as novel platforms for the study of lung diseases (e.g., interstitial lung diseases, fibrosis, influenza, RSV) as well as smoke- and smoking-related diseases. The artificial tissue constructs of the present invention comprise the two components of alveolar tissue, epithelial and endothelial cell layers.
Public/Granted literature
- US20090075282A1 ARTIFICIAL TISSUE CONSTRUCTS COMPRISING ALVEOLAR CELLS AND METHODS FOR USING THE SAME Public/Granted day:2009-03-19
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