Invention Grant
- Patent Title: Promiscuous PAP CD4 T cell epitopes
- Patent Title (中): 混杂PAP CD4 T细胞表位
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Application No.: US13734560Application Date: 2013-01-04
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Publication No.: US08647865B2Publication Date: 2014-02-11
- Inventor: Jami B. Wollan , Lori A. Jones
- Applicant: Dendreon Corporation
- Applicant Address: US WA Seattle
- Assignee: Dendreon Corporation
- Current Assignee: Dendreon Corporation
- Current Assignee Address: US WA Seattle
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/00
Abstract:
The present invention relates to the discovery of novel T cell epitopes of the human prostatic acid phosphatase (PAP) protein that is promiscuous for at least 15 different HLA-DR alleles. The invention also relates to compositions that contain one of the novel epitopes or a fusion peptide of such an epitope and a heterologous polypeptide. Further disclosed herein is the use of the epitopes or their fusion peptides, and compositions containing the epitopes or their fusion peptides.
Public/Granted literature
- US20130203163A1 PROMISCUOUS PAP CD4 T CELL EPITOPES Public/Granted day:2013-08-08
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