Invention Grant
- Patent Title: Prevention of chlamydia infection using SIRNA
- Patent Title (中): 使用SIRNA预防衣原体感染
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Application No.: US11868788Application Date: 2007-10-08
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Publication No.: US08648052B2Publication Date: 2014-02-11
- Inventor: Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki , Madhuri Wadehra-Dhawan , Kathy A. Kelly
- Applicant: Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki , Madhuri Wadehra-Dhawan , Kathy A. Kelly
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Morgan, Lewis & Bockius LLP
- Agent Annette S. Parent
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K39/118

Abstract:
The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The compositions include EMP2 nucleic acids and polypeptides as well as anti-EMP2 antibodies.
Public/Granted literature
- US20080181889A1 PREVENTION OF CHLAMYDIA INFECTION USING A PROTECTIVE ANTIBODY Public/Granted day:2008-07-31
Information query
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