Invention Grant
- Patent Title: Hydrazonamide compounds that modulate Hsp90 activity
- Patent Title (中): 调节Hsp90活性的肼酰胺化合物
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Application No.: US13001255Application Date: 2009-06-26
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Publication No.: US08648071B2Publication Date: 2014-02-11
- Inventor: Joseph Burlison , Dinesh U. Chimmanamada , Weiwen Ying , Shijie Zhang , David James
- Applicant: Joseph Burlison , Dinesh U. Chimmanamada , Weiwen Ying , Shijie Zhang , David James
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- International Application: PCT/US2009/003825 WO 20090626
- International Announcement: WO2009/158026 WO 20091230
- Main IPC: A61K31/5375
- IPC: A61K31/5375 ; A61K31/5377 ; A61K31/445 ; A61K31/357 ; C07D413/00 ; C07D413/02 ; C07D295/00 ; C07D211/00 ; C07D317/46
Abstract:
The present invention relates to substituted hydrazonamide compounds. The invention further relates to methods of inhibiting the activity of Hsρ90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted hydrazonamide compound of the invention, or a pharmaceutical composition comprising such a compound.
Public/Granted literature
- US20120046288A1 Hydrazonamide Compounds That Modulate Hsp90 Activity Public/Granted day:2012-02-23
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