Invention Grant
US08648084B2 Selective substituted pyrazine ligands for neuronal nicotinic receptors
有权
用于神经元烟碱受体的选择性取代吡嗪配体
- Patent Title: Selective substituted pyrazine ligands for neuronal nicotinic receptors
- Patent Title (中): 用于神经元烟碱受体的选择性取代吡嗪配体
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Application No.: US13413138Application Date: 2012-03-06
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Publication No.: US08648084B2Publication Date: 2014-02-11
- Inventor: William H. Bunnelle , Lei Shi , Marc J. C. Scanio
- Applicant: William H. Bunnelle , Lei Shi , Marc J. C. Scanio
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Michael Best & Friedrich, LLP
- Agent Lisa V. Mueller
- Main IPC: A61K31/4965
- IPC: A61K31/4965
Abstract:
The present application describes selective ligands of formula (I) for neuronal nicotinic receptors (NNRs), more specifically for the α4β2 NNR subtype, compositions thereof, and methods of using the same, wherein X, R1, X, R2, R3, L1, m, n, p, and q are defined in the specification.
Public/Granted literature
- US20120190692A1 SELECTIVE SUBSTITUTED PYRIDINE LIGANDS FOR NEURONAL NICOTINIC RECEPTORS Public/Granted day:2012-07-26
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