Invention Grant
- Patent Title: Use of transplatin to prevent hearing loss
- Patent Title (中): 使用转铁蛋白来预防听力损失
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Application No.: US12836398Application Date: 2010-07-14
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Publication No.: US08648114B2Publication Date: 2014-02-11
- Inventor: Vickram Ramkumar , Debashree Mukherjea , Len Rybak
- Applicant: Vickram Ramkumar , Debashree Mukherjea , Len Rybak
- Applicant Address: US IL Carbondale
- Assignee: The Board of Trustees of the Southern Illinois University
- Current Assignee: The Board of Trustees of the Southern Illinois University
- Current Assignee Address: US IL Carbondale
- Agency: Polsinelli PC
- Main IPC: A01N55/02
- IPC: A01N55/02 ; A61K31/28 ; A61K33/24
Abstract:
Methods and compositions for treating and preventing toxic side effects of platinum-based chemotherapy agents are disclosed, in which transplatin is administered to a subject. Transplatin is shown to have protective effects against cisplatin-induced ototoxicity, nephotoxicity and neurotoxicity. Anti-inflammatory activity of transplatin is demonstrated and methods and compositions for treating and preventing inflammatory pain are described.
Public/Granted literature
- US20110014302A1 USE OF TRANSPLATIN TO PREVENT HEARING LOSS Public/Granted day:2011-01-20
Information query
