Invention Grant
US08648170B2 Peptide-presenting surfaces for long-term culture of pluripotent cells
有权
用于多潜能细胞长期培养的肽呈递表面
- Patent Title: Peptide-presenting surfaces for long-term culture of pluripotent cells
- Patent Title (中): 用于多潜能细胞长期培养的肽呈递表面
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Application No.: US12563009Application Date: 2009-09-18
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Publication No.: US08648170B2Publication Date: 2014-02-11
- Inventor: Laura Lee Kiessling , Joseph Robert Klim , Lingyin Li
- Applicant: Laura Lee Kiessling , Joseph Robert Klim , Lingyin Li
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Quarles & Brady LLP
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K38/06 ; A61K38/00 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; A61K51/00
Abstract:
The present invention relates to methods of growing and maintaining pluripotent cells on an insoluble substrate that presents a peptide that binds to glycosaminoglycans, such as heparin. Specifically, methods of growing and maintaining pluripotent cells on substrates having a chemically defined surface presenting at least one peptide having basic amino acid residues separated by one or two hydrophobic amino acid residues.
Public/Granted literature
- US20100087004A1 PEPTIDE-PRESENTING SURFACES FOR LONG-TERM CULTURE OF PLURIPOTENT CELLS Public/Granted day:2010-04-08
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