Invention Grant
US08648197B2 Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists
失效
用作趋化因子受体拮抗剂的取代的哌嗪基 - 吡咯烷化合物
- Patent Title: Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists
- Patent Title (中): 用作趋化因子受体拮抗剂的取代的哌嗪基 - 吡咯烷化合物
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Application No.: US13429575Application Date: 2012-03-26
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Publication No.: US08648197B2Publication Date: 2014-02-11
- Inventor: Kenneth G. Carson , Shomir Ghosh , Prakash Raman , Francois Soucy , Qing Ye
- Applicant: Kenneth G. Carson , Shomir Ghosh , Prakash Raman , Francois Soucy , Qing Ye
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Millennium Pharmaceuticals, Inc.
- Main IPC: C07D401/00
- IPC: C07D401/00 ; A61K31/535
Abstract:
The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer or osteolytic bone disorders.
Public/Granted literature
- US20130123270A1 SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS Public/Granted day:2013-05-16
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