According to one embodiment, a plaque region extracting apparatus includes a blood vessel wall data extracting unit, an intermediate image data generating unit, an enhancement processing unit, a plaque extracting unit. The blood vessel wall data extracting unit extracts first image data including a blood vessel wall from image data acquired by imaging a subject including blood vessels. The intermediate image data generating unit filters an intermediate region in the first image data to generate intermediate second image data. The enhancement processing unit processes the difference between the first image data and the second image data to generate third image data. The plaque extracting unit extracts a plaque in the blood vessel on the basis of the third image data.