Systems, methods, and apparatus for sampling images using minimum mean square error subpixel-based down-sampling are presented herein. A partition component can be configured to divide a first array of pixels into two-dimensional (2-D) blocks of pixels. A sampling component can be configured to receive a query from a device including information associated with a display of the device; diagonally down-sample subpixels of a block of the 2-D blocks and generate a second array of pixels based on the down-sampled subpixels and the query. The sampling component can communicate at least a portion of the second array to the device based on the query. The information associated with the display can include a dimension associated with the display. Further, sampling component can be associated with a web browser; and the query can include an internet based query.