Invention Grant
US08652458B2 Tissue graft with non-aligned fiber matrix retains mesenchymal progenitor cells on the non-injury-facing side
有权
使用非对齐纤维基质的组织移植物在非损伤侧保留间充质祖细胞
- Patent Title: Tissue graft with non-aligned fiber matrix retains mesenchymal progenitor cells on the non-injury-facing side
- Patent Title (中): 使用非对齐纤维基质的组织移植物在非损伤侧保留间充质祖细胞
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Application No.: US13129636Application Date: 2009-08-05
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Publication No.: US08652458B2Publication Date: 2014-02-18
- Inventor: Wesley M. Jackson , Leon J. Nesti , Rocky S. Tuan
- Applicant: Wesley M. Jackson , Leon J. Nesti , Rocky S. Tuan
- Applicant Address: US MD Bethesda US DC Washington US DC Washington
- Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.,The United States of America, as represented by the Secretary of the Army, U.S.A.,The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.,The United States of America, as represented by the Secretary of the Army, U.S.A.,The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US MD Bethesda US DC Washington US DC Washington
- Agency: Foley & Lardner LLP
- International Application: PCT/US2009/004482 WO 20090805
- International Announcement: WO2010/062297 WO 20100603
- Main IPC: A61F2/02
- IPC: A61F2/02
Abstract:
A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested from debrided muscle tissue following orthopaedic trauma. The traumatized muscle-derived progenitor cells are a readily available autologous cell source that can be utilized to effect or improve wound healing in a variety of therapeutic settings and vehicles.
Public/Granted literature
- US20110318414A1 REGENERATIVE TISSUE GRAFTS AND METHODS OF MAKING SAME Public/Granted day:2011-12-29
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