Invention Grant
US08652487B2 Tolerogenic synthetic nanocarriers for inducing regulatory B cells
有权
用于诱导调节性B细胞的耐受性合成纳米载体
- Patent Title: Tolerogenic synthetic nanocarriers for inducing regulatory B cells
- Patent Title (中): 用于诱导调节性B细胞的耐受性合成纳米载体
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Application No.: US13458179Application Date: 2012-04-27
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Publication No.: US08652487B2Publication Date: 2014-02-18
- Inventor: Roberto A. Maldonado
- Applicant: Roberto A. Maldonado
- Applicant Address: US MA Watertown
- Assignee: Selecta Biosciences, Inc.
- Current Assignee: Selecta Biosciences, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/18 ; C07K16/16 ; A61K9/51 ; A61K9/58 ; A61K47/00 ; A61K9/14
Abstract:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising B cell and/or MHC Class II-restricted epitopes and immunosuppressants in order to generate tolerogenic immune responses, such as the generation of antigen-specific regulatory B cells.
Public/Granted literature
- US20120276133A1 TOLEROGENIC SYNTHETIC NANOCARRIERS FOR INDUCING REGULATORY B CELLS Public/Granted day:2012-11-01
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