Invention Grant
US08652540B2 Method of using rhein for treating fibrotic conditions and tumors
有权
使用大黄酸治疗纤维化病症和肿瘤的方法
- Patent Title: Method of using rhein for treating fibrotic conditions and tumors
- Patent Title (中): 使用大黄酸治疗纤维化病症和肿瘤的方法
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Application No.: US13831990Application Date: 2013-03-15
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Publication No.: US08652540B2Publication Date: 2014-02-18
- Inventor: Zhaoxiang Bian , Siu Wai Tsang , Aiping Lu , Haitao Xiao , Hongyan Qin , Albert Sun-Chi Chan , Hongxi Xu , Shilin Chen , Dajian Yang
- Applicant: Hong Kong Baptist University
- Applicant Address: HK Kowloon Tong, Kowloon
- Assignee: Hong Kong Baptist University
- Current Assignee: Hong Kong Baptist University
- Current Assignee Address: HK Kowloon Tong, Kowloon
- Agency: Ella Cheong Hong Kong
- Agent Sam T. Yip
- Main IPC: A01N65/00
- IPC: A01N65/00
Abstract:
The present invention relates to a method of using an anthraquinone derivative namely 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, or known as Rhein, for treating chronic pancreatitis induced fibrosis of the pancreas. More particularly, the present invention relates to a method of using Rhein, its derivatives and/or chemical variants as an anti-fibrotic agent. The present invention particularly relates to the suppression of pancreatic stellate cell activation for the management of chronic inflammatory, fibrotic and tumorigenic pathologies in the pancreas.
Public/Granted literature
- US20130323329A1 Method Of Using Rhein For Treating Fibrotic Conditions And Tumors Public/Granted day:2013-12-05
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