Invention Grant
- Patent Title: Prediction of QT prolongation based on SNP genotype
- Patent Title (中): 基于SNP基因型的QT延长预测
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Application No.: US12675607Application Date: 2008-09-10
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Publication No.: US08652776B2Publication Date: 2014-02-18
- Inventor: Christian Lavedan , Simona Volpi , Louis Licamele , Kendra Tomino Mack , Callie Michelle Heaton
- Applicant: Christian Lavedan , Simona Volpi , Louis Licamele , Kendra Tomino Mack , Callie Michelle Heaton
- Applicant Address: US DC Washington
- Assignee: Vanda Pharmaceuticals, Inc.
- Current Assignee: Vanda Pharmaceuticals, Inc.
- Current Assignee Address: US DC Washington
- Agency: Hoffman Warnick LLC
- International Application: PCT/US2008/075905 WO 20080910
- International Announcement: WO2009/036100 WO 20090319
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04
Abstract:
The present invention relates to the prediction of QT prolongation following administration of a compound capable of increasing an individual's QT interval based on the individual's genotype at one or more single nucleotide polymorphism (SNP) loci and to the treatment of a patient based on such prediction.
Public/Granted literature
- US20100249188A1 PREDICTION OF QT PROLONGATION BASED ON SNP GENOTYPE Public/Granted day:2010-09-30
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