Invention Grant
- Patent Title: Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
- Patent Title (中): 包含脱氧胆酸及其盐的组合物适用于治疗脂肪沉积物
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Application No.: US13207337Application Date: 2011-08-10
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Publication No.: US08653058B2Publication Date: 2014-02-18
- Inventor: Robert Emil Hodge , Jeffrey Douglas Webster , Robert M. Moriarty
- Applicant: Robert Emil Hodge , Jeffrey Douglas Webster , Robert M. Moriarty
- Applicant Address: US CA Calabasas
- Assignee: Kythera Biopharmaceuticals, Inc.
- Current Assignee: Kythera Biopharmaceuticals, Inc.
- Current Assignee Address: US CA Calabasas
- Agency: Foley & Lardner LLP
- Main IPC: A61K31/56
- IPC: A61K31/56
Abstract:
The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
Public/Granted literature
- US20120258943A1 FORMULATIONS OF DEOXYCHOLIC ACID AND SALTS THEREOF Public/Granted day:2012-10-11
Information query
