Invention Grant
- Patent Title: Process for synthesizing heterocyclic compounds
- Patent Title (中): 杂环化合物合成方法
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Application No.: US12026746Application Date: 2008-02-06
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Publication No.: US08653259B2Publication Date: 2014-02-18
- Inventor: Uwe Heinelt , Hans-Jochen Lang
- Applicant: Uwe Heinelt , Hans-Jochen Lang
- Applicant Address: DE Frankfurt am Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: DE10323701 20030522
- Main IPC: C07D233/50
- IPC: C07D233/50 ; C07D235/20 ; C07D235/04 ; C07D235/02 ; C07D263/28 ; C07D263/58 ; C07D263/52 ; C07D265/08 ; C07D265/06 ; C07D265/12 ; C07D265/18 ; C07D277/18 ; C07D277/08 ; C07D409/12 ; C07D409/02 ; C07D413/12 ; C07D495/04 ; C07D233/06

Abstract:
The invention provides the process illustrated in scheme 1 for synthesizing heterocyclic compounds of formula I. In the process, an isothiocyanate of formula II is initially reacted with a primary amine or formula III to give a thiourea of formula IV. Subsequently, the thiourea of formula IV is converted to the corresponding heterocycle of formula I using a base and a sulfonyl chloride.
Public/Granted literature
- US20080146797A1 PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS Public/Granted day:2008-06-19
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