Invention Grant
US08653263B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators
有权
二取代八氢吡咯并[3,4-c]吡咯作为食欲素受体调节剂
![Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators](/docs/US/2014-02-18/US08653263B2/abs.jpg.600x600.jpg)
- Patent Title: Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators
- Patent Title (中): 二取代八氢吡咯并[3,4-c]吡咯作为食欲素受体调节剂
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Application No.: US13503231Application Date: 2010-10-21
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Publication No.: US08653263B2Publication Date: 2014-02-18
- Inventor: Wenying Chai , Michael A. Letavic , Kiev S. Ly , Daniel J. Pippel , Dale A. Rudolph , Kathleen C. Sappey , Brad M. Savall , Chandravadan R. Shah , Brock T. Shireman , Akinola Soyode-Johnson , Emily M. Stocking , Devin M. Swanson
- Applicant: Wenying Chai , Michael A. Letavic , Kiev S. Ly , Daniel J. Pippel , Dale A. Rudolph , Kathleen C. Sappey , Brad M. Savall , Chandravadan R. Shah , Brock T. Shireman , Akinola Soyode-Johnson , Emily M. Stocking , Devin M. Swanson
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica
- Current Assignee: Janssen Pharmaceutica
- Current Assignee Address: BE
- International Application: PCT/US2010/053606 WO 20101021
- International Announcement: WO2011/050198 WO 20110428
- Main IPC: C07D417/00
- IPC: C07D417/00 ; C07D239/02 ; C07D241/36 ; C07D215/38 ; A61K31/4965 ; A61K31/515 ; A61K31/44 ; A61K31/425
![Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators](/abs-image/US/2014/02/18/US08653263B2/abs.jpg.150x150.jpg)
Abstract:
Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.
Public/Granted literature
- US20120208812A1 DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLES AS OREXIN RECEPTOR MODULATORS Public/Granted day:2012-08-16
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