Invention Grant
- Patent Title: Preparation method of rosuvastatin calcium and its intermediates
- Patent Title (中): 罗苏伐他汀钙及其中间体的制备方法
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Application No.: US12994520Application Date: 2009-05-27
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Publication No.: US08653265B2Publication Date: 2014-02-18
- Inventor: Benshun Chen , Bing Wang , Xiaofeng Jin , Lin Zou
- Applicant: Benshun Chen , Bing Wang , Xiaofeng Jin , Lin Zou
- Applicant Address: CN Jiangsu
- Assignee: Changzhou Pharmaceutical Factory
- Current Assignee: Changzhou Pharmaceutical Factory
- Current Assignee Address: CN Jiangsu
- Agency: Patterson Thuente Pedersen, P.A.
- Priority: CN200810110709 20080527; CN200810110711 20080527
- International Application: PCT/CN2009/072018 WO 20090527
- International Announcement: WO2009/143776 WO 20091203
- Main IPC: C07D239/02
- IPC: C07D239/02
Abstract:
A preparation method of rosuvastatin calcium (Formula 1), which can be used for the production of medicament lowering the levels of LDL-cholesterol and triglycerides in vivo, is provided. Such preparation method is suitable for industrial production. Furthermore, the intermediate crystallines used in the preparation method are provided.
Public/Granted literature
- US20110124864A1 PREPARATION METHOD OF ROSUVASTATIN CALCIUM AND ITS INTERMEDIATES Public/Granted day:2011-05-26
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