Options for safely handling incoming data messages in a moving mobile device are provided within the mobile device. When an incoming data message is detected, the device determines its velocity. If the velocity exceeds a certain value, external data, such as visual or biometric data, measured by a device component is analyzed to determine whether the mobile device is in a driver position of a moving vehicle. If so, an announcement of the incoming call is prevented and a predetermined message is autonomously transmitted to the sender. If analysis of the external data is inconclusive, a prompt is presented to a recipient with selectable options of how to handle the incoming message. In response to the various inputs received from the recipient, the mobile device may either autonomously send a response message to the sender or may directly establish a voice call between the recipient and the sender.