Invention Grant
- Patent Title: Pharmaceutical composition of nanoparticles
- Patent Title (中): 纳米粒子的药物组成
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Application No.: US13682929Application Date: 2012-11-21
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Publication No.: US08663599B1Publication Date: 2014-03-04
- Inventor: Hsing-Wen Sung , Zi-Xian Liao , Min-Fan Chung , Ko-Jie Chen , Po-Yuan Cheng , Hosheng Tu
- Applicant: Hsing-Wen Sung , Zi-Xian Liao , Min-Fan Chung , Ko-Jie Chen , Po-Yuan Cheng , Hosheng Tu
- Applicant Address: US CA Newport Beach TW Hsinchu
- Assignee: GP Medical, Inc.,National Tsing Hua University
- Current Assignee: GP Medical, Inc.,National Tsing Hua University
- Current Assignee Address: US CA Newport Beach TW Hsinchu
- Main IPC: A61K51/00
- IPC: A61K51/00
Abstract:
The invention discloses a pharmaceutical composition of pH-sensitive liposome nanoparticles for lodging in a target tissue cell in situ of an animal subject, the nanoparticles comprising a proton-releasing photosensitive compound that releases protons upon photolysis, wherein the compound is in vesicles of the liposomes. A light or UV light is provided to induce the photosensitive compound to release the protons, thus the released protons causing the pH-sensitive liposome to decompose.
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