Invention Grant
US08663622B2 Recombinant vaccine viruses expressing IL-15 and methods using the same
有权
表达IL-15的重组疫苗病毒及使用其的方法
- Patent Title: Recombinant vaccine viruses expressing IL-15 and methods using the same
- Patent Title (中): 表达IL-15的重组疫苗病毒及使用其的方法
-
Application No.: US10538974Application Date: 2003-12-15
-
Publication No.: US08663622B2Publication Date: 2014-03-04
- Inventor: Liyanage P. Perera , Thomas A. Waldmann , Sang-Kon Oh , Jay A. Berzofsky
- Applicant: Liyanage P. Perera , Thomas A. Waldmann , Sang-Kon Oh , Jay A. Berzofsky
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
- Current Assignee Address: US DC Washington
- Agency: Edwards Wildman Palmer LLP
- Agent Peter F. Corless
- International Application: PCT/US03/39967 WO 20031215
- International Announcement: WO2004/058278 WO 20040715
- Main IPC: A01N63/00
- IPC: A01N63/00
Abstract:
The invention is directed to compositions capable of augmenting the immunogenicity of a vaccine. The composition, or adjuvant, is administered to a mammal in need thereof in sequential or concurrent combination with a vaccine antigen. In one preferred aspect, the adjuvant is provided in the form of a recombinant poxvirus vector, such as a vaccinia virus vector, which comprises a nucleic acid sequence encoding IL-15.
Public/Granted literature
- US20060147419A1 Recombinant vaccine viruses expressing il-15 and methods of using the same Public/Granted day:2006-07-06
Information query
