Invention Grant
US08663678B2 Solid dosage form for the ocular administration of an active principle, a soluble, solid ophthalmic insert and the production method thereof 有权
用于眼部施用活性成分的固体剂型,可溶性固体眼科插入物及其制备方法

Solid dosage form for the ocular administration of an active principle, a soluble, solid ophthalmic insert and the production method thereof
Abstract:
A solid dosage form for the ocular administration of an active principle includes at least one biocompatible, water-soluble excipient for ophthalmic use. The form is obtained using a method which is selected from among the following: direct compression, dry compression, wet compression, compression of a lyophilizate, the compression being carried out a temperature below 45° C., or lyophilization, such that the form can disintegrate and release the active principle in the conjunctival sac. The invention also relates to an ophthalmic insert having the aforementioned dosage form which is appropriately dimensioned for ocular administration.
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