Invention Grant
- Patent Title: Solid dispersion preparation
- Patent Title (中): 固体分散体制备
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Application No.: US13710917Application Date: 2012-12-11
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Publication No.: US08663698B2Publication Date: 2014-03-04
- Inventor: Takafumi Hoshino , Fumie Kusaki , Ikuo Fukui
- Applicant: Shin-Etsu Chemical Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Shin-Etsu Chemical Co., Ltd.
- Current Assignee: Shin-Etsu Chemical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Roberts Mlotkowski Safran & Cole, P.C.
- Agent David S. Safran
- Priority: JP2006-116272 20060420; JP2007-087957 20070329
- Main IPC: A61K9/14
- IPC: A61K9/14

Abstract:
A granule or a tablet of a solid dispersion that allows a drug in a preparation to be rapidly dissolved without impairing dissolving of the solid dispersion, and a method for producing same is composed of 1 to 10% by weight of a poorly soluble drug, a water-soluble polymer, an excipient and 15 to 50% by weight if a disintegrator; a tablet of a solid dispersion composed of a poorly soluble drug, 1 to 5% by weight of a water-soluble polymer, an excipient and 15 to 50% by weight of a disintegrator; and a method for producing a granule or tablet of a solid dispersion comprising spraying a water-soluble polymer solution, in which a poorly soluble drug has been dispersed or dissolved, on a mixed powder of an excipient and a disintegrator, and granulating and drying a resultant.
Public/Granted literature
- US20130171332A1 SOLID DISPERSION PREPARATION Public/Granted day:2013-07-04
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