Invention Grant
- Patent Title: Mesenchymal stem cells for the treatment of CNS diseases
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Application No.: US12994761Application Date: 2009-05-26
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Publication No.: US08663987B2Publication Date: 2014-03-04
- Inventor: Avinoam Kadouri , Avihay Bar-Ilan , Eldad Melamed , Daniel Offen , Ofer Sadan , Merav Bahat-Stromza
- Applicant: Avinoam Kadouri , Avihay Bar-Ilan , Eldad Melamed , Daniel Offen , Ofer Sadan , Merav Bahat-Stromza
- Applicant Address: IL Tel-Aviv IL Petach-Tikva
- Assignee: Ramot at Tel-Aviv University Ltd.,BrainStorm Cell Therapeutics Ltd.
- Current Assignee: Ramot at Tel-Aviv University Ltd.,BrainStorm Cell Therapeutics Ltd.
- Current Assignee Address: IL Tel-Aviv IL Petach-Tikva
- International Application: PCT/IL2009/000525 WO 20090526
- International Announcement: WO2009/144718 WO 20091203
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/079
Abstract:
An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
Public/Granted literature
- US20120009673A1 MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES Public/Granted day:2012-01-12
Information query
