Invention Grant
- Patent Title: Identification of novel antagonist toxins of T-type calcium channel for analgesic purposes
- Patent Title (中): 鉴定T型钙通道的新型拮抗剂毒素用于止痛目的
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Application No.: US13144734Application Date: 2010-01-15
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Publication No.: US08664179B2Publication Date: 2014-03-04
- Inventor: Emmanuel Bourinet , Pierre Escoubas , Fabrice Marger , Joel Nargeot , Michel Lazdunski
- Applicant: Emmanuel Bourinet , Pierre Escoubas , Fabrice Marger , Joel Nargeot , Michel Lazdunski
- Applicant Address: FR Paris FR Nice
- Assignee: Centre National de la Recherche Scientifique (CNRS),Universite de Nice Sophia Antipolis
- Current Assignee: Centre National de la Recherche Scientifique (CNRS),Universite de Nice Sophia Antipolis
- Current Assignee Address: FR Paris FR Nice
- Agency: Young & Thompson
- Priority: FR0900174 20090115
- International Application: PCT/FR2010/000037 WO 20100115
- International Announcement: WO2010/081971 WO 20100722
- Main IPC: C07K14/00
- IPC: C07K14/00
Abstract:
A peptide with the following sequence YCQKFLWTCDSERPCCEGLVCRLWCKIN (SEQ ID NO 1) or a derivative thereof, and nucleic acids coding for the peptide having the sequence (SEQ ID NO 1). Also the use of this peptide as an antagonist and/or reverse agonist of T-type calcium channels. A use of the peptide for preparing a drug, in particular an analgesic one.
Public/Granted literature
- US20120040909A1 IDENTIFICATION OF NOVEL ANTAGONIST TOXINS OF T-TYPE CALCIUM CHANNEL FOR ANALGESIC PURPOSES Public/Granted day:2012-02-16
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