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US08664230B2 Pyridopyrimidine derivatives and use thereof 有权
吡啶并嘧啶衍生物及其用途

Pyridopyrimidine derivatives and use thereof
Abstract:
The invention provides novel substituted pyridopyrimidines represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ OH kinase family (PI3K) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders.
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