Invention Grant
- Patent Title: Process for the preparation and purification of amorolfine hydrochloride
- Patent Title (中): 盐酸阿莫罗芬的制备和纯化方法
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Application No.: US13202502Application Date: 2010-02-18
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Publication No.: US08664381B2Publication Date: 2014-03-04
- Inventor: Roberto Angeli , Marco Possenti , Salvatore Demartis
- Applicant: Roberto Angeli , Marco Possenti , Salvatore Demartis
- Applicant Address: IT San Martino Siccomario
- Assignee: SYNTECO S.p.A.
- Current Assignee: SYNTECO S.p.A.
- Current Assignee Address: IT San Martino Siccomario
- Agency: Abelman, Frayne & Schwab
- Priority: ITFI2009A0032 20090220
- International Application: PCT/EP2010/052047 WO 20100218
- International Announcement: WO2010/094739 WO 20100826
- Main IPC: C07D265/30
- IPC: C07D265/30

Abstract:
The present invention relates to a process for the purification of amorolfine hydrochloride by means of a reversed-phase preparative high performances liquid chromatography (prep-HPLC) said method starting from a crude Amorolfine hydrochloride having purity higher than 90% and containing Bepromoline hydrochloride
Public/Granted literature
- US20110301346A1 PROCESS FOR THE PURIFICATION OF AMOROLFINE HYDROCHLORIDE Public/Granted day:2011-12-08
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