Invention Grant
- Patent Title: Pyrazine derivatives for bioconjugation
- Patent Title (中): 吡嗪衍生物用于生物共轭
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Application No.: US13344930Application Date: 2012-01-06
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Publication No.: US08664392B2Publication Date: 2014-03-04
- Inventor: Raghavan Rajagopalan , Richard B. Dorshow
- Applicant: Raghavan Rajagopalan , Richard B. Dorshow
- Applicant Address: US MO St. Louis
- Assignee: MediBeacon, LLC
- Current Assignee: MediBeacon, LLC
- Current Assignee Address: US MO St. Louis
- Agent Dennis A. Bennett; Gale W. Starkey
- Main IPC: C07D241/02
- IPC: C07D241/02 ; A61K31/497 ; A61K31/4965
Abstract:
Provided are compounds and compositions of general Formula IX: E1-L-Ar—X-PA, that may be utilized in bioconjugation procedures, where Ar is a chromophore and PA is a functional group capable of being attached to any bioactive molecule of interest. The present invention provides Formulas I-III that are capable of being attached to a bioactive vector for the selective delivery of said photoactive pyrazine derivatives to a desired biological target.
Public/Granted literature
- US20120134930A1 Pyrazine Derivatives for Bioconjugation Public/Granted day:2012-05-31
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