Invention Grant
- Patent Title: Reagents and methods for detecting influenza virus proteins
- Patent Title (中): 用于检测流感病毒蛋白质的试剂和方法
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Application No.: US12920838Application Date: 2009-03-10
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Publication No.: US08669046B2Publication Date: 2014-03-11
- Inventor: Xuguang (Sean) Li , Runtao He , Gary Van Domselaar
- Applicant: Xuguang (Sean) Li , Runtao He , Gary Van Domselaar
- Agency: Ade & Company Inc.
- Agent Michael R. Williams
- International Application: PCT/CA2009/000283 WO 20090310
- International Announcement: WO2009/111865 WO 20090917
- Main IPC: C07K16/10
- IPC: C07K16/10 ; G01N33/569 ; C07K7/08 ; C07K17/06 ; C12Q1/70 ; A61K39/145

Abstract:
Antibodies that specifically bind to a peptide having an amino acid sequence as found at the N-terminus of the HA2 fusion peptide of the influenza A virus may be raised by inoculating a mammal with a conjugate of the peptide. In one embodiment, the conjugate comprises the peptide linked to a spacer (e.g. 6-aminocaproic acid) and a carrier protein (e.g. KLH). The antibodies may be used as a universal reagent for detecting HA proteins of influenza viruses. The antibodies are useful as versatile reagents for laboratory research and vaccine potency determination, especially in the event of pandemic influenza outbreaks.
Public/Granted literature
- US20110059472A1 REAGENTS AND METHODS FOR DETECTING INFLUENZA VIRUS PROTEINS Public/Granted day:2011-03-10
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