Invention Grant
- Patent Title: BCR-complex-specific antibodies and methods of using same
- Patent Title (中): BCR-复合物特异性抗体及其使用方法
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Application No.: US12933882Application Date: 2009-03-25
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Publication No.: US08669349B2Publication Date: 2014-03-11
- Inventor: Leslie Johnson , Ling Huang
- Applicant: Leslie Johnson , Ling Huang
- Applicant Address: US MD Rockville
- Assignee: MacroGenics, Inc.
- Current Assignee: MacroGenics, Inc.
- Current Assignee Address: US MD Rockville
- Agency: AuerbachSchrot LLC
- Agent William C. Schrot; Jeffrey I. Auerbach
- International Application: PCT/US2009/038171 WO 20090325
- International Announcement: WO2009/151717 WO 20091217
- Main IPC: C07K16/46
- IPC: C07K16/46 ; A61K39/395 ; C07H21/04

Abstract:
This invention relates to chimeric and humanized antibodies that specifically bind the BCR complex, and particularly chimeric and humanized antibodies to the BCR complex. The invention also relates to methods of using the antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious disease.
Public/Granted literature
- US20110117089A1 BCR-Complex-Specific Antibodies And Methods Of Using Same Public/Granted day:2011-05-19
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