Invention Grant
US08669369B2 Method and process for preparation and production of deuterated Ω-diphenylurea
有权
氘代欧米加二苯脲的制备和生产方法和方法
- Patent Title: Method and process for preparation and production of deuterated Ω-diphenylurea
- Patent Title (中): 氘代欧米加二苯脲的制备和生产方法和方法
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Application No.: US13635822Application Date: 2011-03-17
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Publication No.: US08669369B2Publication Date: 2014-03-11
- Inventor: Weidong Feng , Xiaoyong Gao , Xiaojun Dai
- Applicant: Weidong Feng , Xiaoyong Gao , Xiaojun Dai
- Applicant Address: CN Jiangsu
- Assignee: Suzhou Zelgen Biopharmaceutical Co., Ltd.
- Current Assignee: Suzhou Zelgen Biopharmaceutical Co., Ltd.
- Current Assignee Address: CN Jiangsu
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: CN201010127706 20100318
- International Application: PCT/CN2011/071926 WO 20110317
- International Announcement: WO2011/113367 WO 20110922
- Main IPC: C07D213/63
- IPC: C07D213/63 ; C07C209/68 ; C07D207/408 ; C07D213/81
Abstract:
Methods and processes for preparation and production of deuterated ω-diphenylurea are disclosed. Especially, a kind of deuterated ω-diphenylurea compounds which can inhibit phosphokinase and the preparation method of N-(4-chloro-3-(trifluoromethyl)phenyl)-N′-(4-(2-(N-d3-methylcarbamoyl)-4-pridinyloxy)phenyl)urea are disclosed. The said deuterated diphenylurea compounds can be used for treating or preventing tumors and relative diseases.
Public/Granted literature
- US20130035492A1 METHOD AND PROCESS FOR PREPARATION AND PRODUCTION OF DEUTERATED OMEGA-DIPHENYLUREA Public/Granted day:2013-02-07
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