Invention Grant
- Patent Title: Cytotoxin compounds and methods of isolation
- Patent Title (中): 细胞毒素化合物和分离方法
-
Application No.: US12066938Application Date: 2006-09-18
-
Publication No.: US08669376B2Publication Date: 2014-03-11
- Inventor: Bill Baker , Thushara Diyabalanage , James B. McClintock , Charles D. Amsler
- Applicant: Bill Baker , Thushara Diyabalanage , James B. McClintock , Charles D. Amsler
- Applicant Address: US FL Tampa US AL Birmingham
- Assignee: University of South Florida,The UAB Research Foundation
- Current Assignee: University of South Florida,The UAB Research Foundation
- Current Assignee Address: US FL Tampa US AL Birmingham
- Agency: Saliwanchik, Lloyd & Eisenschenk
- International Application: PCT/US2006/036484 WO 20060918
- International Announcement: WO2007/035734 WO 20070329
- Main IPC: C07D313/00
- IPC: C07D313/00 ; C12N9/99 ; A61K31/335 ; A61P35/00
Abstract:
The present invention concerns groups of compounds derived from tunicates of the Synoicum species, as well as to pharmaceutical compositions comprising these compounds, and uses thereof. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines.
Public/Granted literature
- US20090192215A1 Cytotoxin Compounds and Methods of Isolation Public/Granted day:2009-07-30
Information query
