A wheat variety designated XW10S, the plants and seeds of wheat variety XW10S, methods for producing a wheat plant produced by crossing the variety XW10S with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety XW10S with another wheat line or plant, and the creation of variants by mutagenesis or transformation of variety XW10S. This invention also relates to methods for producing other wheat varieties or breeding lines derived from wheat variety XW10S and to wheat varieties or breeding lines produced by those methods.