A particle beam target for producing radionuclides includes a target body, a target cavity, parallel grooves, peripheral bores, and radial outflow bores. The parallel grooves are formed in a back side of the target body and include respective first and second groove ends. The peripheral bores extend through the target body from the plurality of grooves generally toward the front side that receives a particle beam. Each groove communicates with a peripheral bore at the first groove end and another peripheral bore at the second groove end. The radial outflow bores extend radially from the plurality of peripheral bores. The target body defines a plurality of liquid coolant flow paths. Each liquid coolant flow path runs from a respective groove to at least one of the first groove end and the second groove end of the respective groove, through at least one peripheral bore, and through at least one radial outflow bore.